Siyin Liu
PhD student
Background
I am currently an MRC/Fight for Sight Clinical Research Fellow at the UCL Institute of Ophthalmology and an ophthalmologist at Moorfields Eye Hospital. Prior to this role, I was an NIHR Academic Clinical Fellow and an Ophthalmology Registrar at Manchester Royal Eye Hospital. My research focuses on integrating molecular discoveries with clinical data to improve patient outcomes. My present work aims at gaining a deeper understanding of the genetic factors that drive the onset and progression of Fuchs' Endothelial Corneal Dystrophy (FECD), the most prevalent short-tandem repeat expansion-associated disorder characterized in humans to date. Using innovative genotyping techniques and advanced clinical imaging, we aim to discover new molecular insights with clinical relevance, which will ultimately allow for the development of decision support systems that can help to guide personalized medicine and improve risk stratification approaches.
